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HPV18 1. Physics and Chemical Physics, M.

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Bingyun Li Ph. Although there have been several population-based cervical cancer screening programs in China, the majority of the population, especially those in rural areas, do not have access to regular screenings. Published online Mar Approximately 14 genotypes of HPV HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68 are closely associated with cervical, anogenital, and oropharyngeal cancers [ 9 , 10 ], which, as a result, are classified as high-risk HPV hrHPV genotypes [ 11 ]. Methods HPV testing results of 94, females were retrospectively reviewed and extracted from the database of Jinan KingMed Diagnostics, the largest independent pathology laboratory in Shandong Province, China. Received Oct 10; Accepted Dec Eman M. Although several studies have been conducted in a few cities of Shandong Province, such as Jinan [ 24 ], Qingdao [ 26 ], Dongying [ 27 ], and Weihai [ 28 , 29 ], the available data are still insufficient and the HPV-positive rates reported in different studies are inconsistent. HPV16 5. Currently, several long-term, prospective, controlled trials [ 14 — 17 ] have confirmed that hrHPV testing detects significantly more cervical cancer and its precursors, therefore resulting in lower rates of invasive cancer in subsequent rounds of screening compared with cytology. Finally, the selection pressures of the E6-E7 and L1 genes were estimated. Simply email us your document or use our online submission page. The HPV genotyping results and relevant clinical information, including age and clinical history available in the pathology database, were all recorded.

Sc, Monash University, Australia. Moreover, the improved negative predictive value of HPV testing, which significantly exceeds that of cervical cytology, allows the cervical cancer screening intervals to be safely extended from 3 years to 5 years [ 1819 ].

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